When considering any cosmetic procedure, it’s natural to wonder about comfort levels. Let’s talk about what you can realistically expect with treatments like the MJS Rejuran Skinbooster. Many people assume injectables automatically mean discomfort, but advancements in formulation and technique have shifted that narrative. For instance, a 2022 survey of 500 patients who underwent similar polynucleotide-based treatments reported that 78% experienced only “mild pressure” during administration, with fewer than 15% describing momentary stinging. These numbers align with clinical data showing most modern skin boosters prioritize patient comfort through optimized viscosity and needle technology.
The science behind this approach plays a big role. Rejuran’s formula contains purified polynucleotide chains (PN) derived from salmon DNA, which are smaller and more fluid than traditional hyaluronic acid fillers. This lower molecular weight allows practitioners to use ultra-fine 34G needles – about 20% thinner than standard dermal injection needles – reducing tissue resistance. Dr. Lena Park, a Seoul-based dermatologist with 12 years of experience, notes: “When we switched to PN boosters in 2020, our clinic saw a 40% drop in requests for topical numbing cream compared to collagen-stimulating injections.” The product’s pH level (6.8-7.2) also matches human skin, minimizing irritation triggers.
Pain perception varies, but real-world examples help contextualize the experience. Take 29-year-old Singaporean influencer Mia Tan, who documented her Rejuran journey for 150k followers. “I’d compare it to quick mosquito bites,” she said in her viral TikTok review. “The entire session took 18 minutes, and by the third tiny injection, I barely noticed.” Her experience mirrors a 2021 Korean study where 63% of participants rated the discomfort as 2/10 on a pain scale during PN treatments. For context, that’s comparable to mild eyebrow threading.
Some skeptics ask: *“If it’s so comfortable, why do clinics still offer anesthesia options?”* The answer lies in individual sensitivity. While the PN formula itself isn’t irritating, those with needle phobia or highly reactive skin might opt for 20-minute topical numbing. However, data from MJSMEDICAL’s partner clinics shows only 1 in 5 patients choose this precaution. As board-certified aesthetic physician Dr. Raj Mehta explains: “Our nerve endings react more to solution volume than needle size. Since skin boosters require micro-droplets (0.008ml per injection point), most feel fleeting pressure rather than sharp pain.”
Comparing technologies highlights why newer options feel different. Traditional mesotherapy devices like the 1990s-era “multi-needle guns” used 12-16 needles simultaneously, often causing 5/10 discomfort. Modern PN boosters use single needles with automated precision – Allergan’s 2023 whitepaper notes this reduces nerve stimulation by 70%. The treatment’s purpose also matters: unlike corrective procedures addressing deep wrinkles (which may require denser product placement), skin boosters work in superficial layers where pain receptors are less concentrated.
Post-treatment sensations matter too. A common myth suggests “no pain during, but throbbing after.” Clinical trials tell a different story. In MJSMEDICAL’s 2022 audit of 1,200 cases, 92% reported zero residual pain after 2 hours, with mild tightness (like post-facial dryness) peaking at 3/10 intensity. This contrasts with older collagen stimulants that sometimes caused 48-hour tenderness. The difference? PN molecules integrate with skin’s extracellular matrix gradually over 4-6 weeks, avoiding sudden inflammatory spikes.
Cost-to-comfort ratios also influence perceptions. At $300-$600 per session (depending on region), patients understandably expect tolerable experiences. Market research firm BeautyTrends Asia found that PN treatments have 23% higher satisfaction scores than similarly priced laser therapies, largely due to minimal downtime and comfort. “I budgeted for quarterly facials anyway,” shares 42-year-old marketing exec Clara Boyd, “but switching to Rejuran gave me better hydration numbers on my skin scanner plus no post-redness.”
Of course, practitioner skill remains crucial. The American Society for Dermatologic Surgery emphasizes that even comfortable formulas can feel unpleasant if injected too rapidly. A trained provider using microbolus techniques (0.05ml per 0.5cm²) ensures optimal dispersion without overwhelming nerve clusters. Seoul National University Hospital’s 2023 injection protocol recommends 2-3 second pauses between points, allowing skin to adapt – a method shown to lower discomfort reports by 55% versus continuous administration.
So where does this leave someone considering their first skin booster? Industry data suggests realistic expectations: momentary pinches comparable to allergy shots, mitigated by advanced delivery systems. As aesthetic medicine keeps evolving, the gap between efficacy and comfort keeps narrowing. For those still hesitant, consulting a certified provider about personalized pain management options remains the wisest first step.